-Nanomedicina1a–Texto escrito por mim sobre a Nanomedicina @#*& Text I wrote about Nanomedicine
-The Jackson Laboratory, founded in 1929, is an independent, 501(c)3 nonprofit biomedical research institution based in Bar Harbor, Maine, with a National Cancer Institute-designated Cancer Center, a facility in Sacramento, Calif., and a genomic medicine institute in Farmington, Conn. It employs more than 2,100 staff, and its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health. https://en.wikipedia.org/wiki/Jackson_Laboratory
-Major contributions to medical science
To date, 26 Nobel prizes are associated with Jackson Laboratory research, education programs and resources. Dr. George Snell won the 1980 Nobel Prize in Physiology or Medicine for providing an in-depth understanding of the immune system’s major histocompatibility complex, making organ transplants possible. Three graduates of the Laboratory’s Summer Student Program have gone on to win the Nobel Prize, and another two dozen Nobel Prizes have been awarded for research conducted using JAX® Mice. Other historic research highlights include:
- Studies by Douglas Coleman leading to the discovery of leptin, central to obesity and diabetes research.
- Elizabeth Russell’s work leading to new treatments for blood and immunological diseases, including performing the first bone marrow transplants in a mammal.
- Investigations by Leroy Stevens into the mechanisms in cells that allow them to develop into different tissues, leading to modern stem cell research.
- David Harrison’s demonstration of rapamycin as the first pharmaceutical intervention proven to extend the lifespan of a mammal.
The Jackson Laboratory (often abbreviated as JAX) is an independent, nonprofit biomedical research institution dedicated to contributing to a future of better health care based on the unique genetic makeup of each individual. With more than 2,100 employees in Bar Harbor, Maine; Sacramento, California; and at a new genomic medicine institute in Farmington, Connecticut; the Laboratory’s mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health. The institution is a National Cancer Institute-designated Cancer Center and has NIH centers of excellence in aging and systems genetics.
The laboratory is also the world’s source for more than 8,000 strains of genetically defined mice, is home of the Mouse Genome Informatics database and is an international hub for scientific courses, conferences, training and education.
- Hosts the Mouse Genome Informatics database, the world’s source for information on mouse genetics and biology.
- Distributes more than 3 million JAX® mice annually to more than 20,000 investigators in at least 50 countries for research and drug discovery.
- Offers more than 7,000 genetically defined strains of JAX® mice to the international research community.
- Provides animal husbandry, reproductive science and in vivo drug efficacy services in a wide range of therapeutic areas for biomedical researchers.
- Conducts over 100 educational seminars and webinars yearly to educate and enable external biomedical researchers.
The Jackson Laboratory is recognized by the IRS as a public charity. According to organization literature, revenue comes primarily from the sale of materials and services (~70%) and from government support (~25%). Less than 5% of 2012 revenue came from charitable donations.
-Contemporary research highlights
- A grant from the National Institute of General Medical Sciences funds the development of new computational tools to understand how multiple genes interact in complex diseases.
- The National Institute on Aging provides $25 million to develop new treatments, future therapies based on precision modeling.
- The National Institutes of Health (NIH) funds phase 2 of the Knockout Mouse Production and Phenotyping Project (KOMP2).
- A charitable contribution of $8,410,000 from the Harold Alfond Foundation will support The Jackson Laboratory’s efforts to enhance cancer diagnostics and treatment in Maine.
- Researchers link mutations to butterfly-shaped pigment dystrophy, an inherited macular disease 
- Jackson Laboratory researchers discover mutation involved in neurodegeneration
- The Jackson Laboratory for Genomic Medicine opens in Farmington, CT.
The Jackson Laboratory Cancer Center
The Jackson Laboratory Cancer Center (JAXCC) first received its National Cancer Institute designation in 1983 in recognition of the foundational cancer research conducted there. The JAXCC is one of seven NCI-designated Cancer Centers with a focus on basic research.
The Jackson Laboratory Cancer Center has a single program, “Genetic Models for Precision Cancer Medicine,” composed of three biological themes: cancer cell robustness, genomic and genetic complexity, and progenitor cell biology. The themes emphasize the systems genetics of cancer and translational cancer genomics, and all are supported by the JAX Cancer Center’s technological initiatives in mouse modeling, genome analytics and quantitative cell biology. https://en.wikipedia.org/wiki/Jackson_Laboratory
The Jackson Laboratory, an INBRE Research Institution Partner, is a non-profit mammalian genetics research institution founded in 1929 in Bar Harbor. It is a pioneer and leading center in functional genomics and interdisciplinary approaches to biological research, with a focus on the mouse as a basic investigative platform. Located six miles from the MDI Biological Laboratory, the Jackson Laboratory has more than 1,700 employees, including a total research staff of over 500.
The Jackson Laboratory has harnessed the genetic diversity within inbred and mutant strains of mice to study the complex genetics of diseases such as cancers, diabetes, glaucoma, and epilepsy. The collaborative Institute for Molecular Biophysics, established in 2003 with NSF EPSCoR funding, brings together scientists in biology, genetics, physics, chemistry, and engineering to investigate cell structures at the nanoscale. Since 1983, the Jackson Laboratory has been an NCI-designated Cancer Center to pursue basic cancer research. The Laboratory is also a major provider of genetic and information resources to the international community. Comprehensive bioinformatics databases offer online access to the latest mouse genetic information.
The Maine INBRE benefits from the contributions of the Jackson Laboratory, which is a leader of biomedical research in the U.S. and Maine. INBRE expands the presence of the MDI Biological Laboratory and the Jackson Laboratory in Maine by creating opportunities for institutional and investigator collaborations, mentorship of students, sharing research resources and knowledge, and sharing experience which contributes to institutional, investigator, and student development for all involved.
Jackson Laboratory faculty serve as student mentors for summer research fellowships and academic year internships. They also serve as adjunct faculty for the University of Maine’s Graduate School of Biomedical Sciences, which is building a critical pipeline of students becoming the state’s future researchers. Senior faculty act as mentors for INBRE funded investigators at other institutions.
The Jackson Laboratory is proud of its role in helping young people from Maine colleges and universities to prepare for careers in biomedical research, and helping to foster a stronger research community in the state that can provide future jobs for these talented and motivated students. https://inbre.maineidea.net/about-inbre/the-jackson-laboratory/
-Example of animal testing (research) / Website