Oncology Accolades – Benjamin Ebert installed as inaugural Canellos Professor of Medicine @& Awards and Achievements # Harvard Medical School #time

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Pathol Res Pract. 2012 Jul 15;208(7):377-81. doi: 10.1016/j.prp.2012.04.006. Epub 2012 Jun 8.

The influence of physical activity in the progression of experimental lung cancer in mice

Renato Batista Paceli 1Rodrigo Nunes CalCarlos Henrique Ferreira dos SantosJosé Antonio CordeiroCassiano Merussi NeivaKazuo Kawano NagaminePatrícia Maluf Cury


Impact_Fator-wise_Top100Science_Journals

GRUPO_AF1 – GROUP AFA1 – Aerobic Physical Activity – Atividade Física Aeróbia – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto

GRUPO AFAN 1 – GROUP AFAN1 – Anaerobic Physical Activity – Atividade Física Anaeróbia – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto

GRUPO_AF2 – GROUP AFA2 – Aerobic Physical Activity – Atividade Física Aeróbia – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto

GRUPO AFAN 2 – GROUP AFAN 2 – Anaerobic Physical Activity – Atividade Física Anaeróbia – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto

Slides – mestrado – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto

CARCINÓGENO DMBA EM MODELOS EXPERIMENTAIS

DMBA CARCINOGEN IN EXPERIMENTAL MODELS

Avaliação da influência da atividade física aeróbia e anaeróbia na progressão do câncer de pulmão experimental – Summary – Resumo – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto

https://pubmed.ncbi.nlm.nih.gov/22683274/

Abstract

Lung cancer is one of the most incident neoplasms in the world, representing the main cause of mortality for cancer. Many epidemiologic studies have suggested that physical activity may reduce the risk of lung cancer, other works evaluate the effectiveness of the use of the physical activity in the suppression, remission and reduction of the recurrence of tumors. The aim of this study was to evaluate the effects of aerobic and anaerobic physical activity in the development and the progression of lung cancer. Lung tumors were induced with a dose of 3mg of urethane/kg, in 67 male Balb – C type mice, divided in three groups: group 1_24 mice treated with urethane and without physical activity; group 2_25 mice with urethane and subjected to aerobic swimming free exercise; group 3_18 mice with urethane, subjected to anaerobic swimming exercise with gradual loading 5-20% of body weight. All the animals were sacrificed after 20 weeks, and lung lesions were analyzed. The median number of lesions (nodules and hyperplasia) was 3.0 for group 1, 2.0 for group 2 and 1.5-3 (p=0.052). When comparing only the presence or absence of lesion, there was a decrease in the number of lesions in group 3 as compared with group 1 (p=0.03) but not in relation to group 2. There were no metastases or other changes in other organs. The anaerobic physical activity, but not aerobic, diminishes the incidence of experimental lung tumors.

https://hms.harvard.edu/news/oncology-accolades?utm_source=twitter&utm_medium=social&utm_campaign=hms-twitter-general

Sem títuloxxxxxxxxxxxxxxxxxSem títuloxxx

´´On Sept. 26, colleagues, friends and family gathered in the Gordon Hall of Medicine at Harvard Medical School to celebrate the installation of blood cancer expert Benjamin Ebert as the inaugural George P. Canellos, MD, and Jean S. Canellos Professor of Medicine at HMS and Dana-Farber Cancer Institute.´´

Get more HMS news here

´´Ebert earned a PhD from Oxford University as a Rhodes Scholar, followed by an MD from HMS in 1999. His training spanned Massachusetts General Hospital, Dana-Farber and the Broad Institute of MIT and Harvard.´´

´´A clinician and scientist, Ebert is widely respected for his contributions to understanding and treating hematologic disorders such as leukemia and myelodysplastic syndrome. His research focuses on uncovering the genetic mutations and mechanisms that underlie such malignancies, with the goal of informing the development of new therapies and better identifying which patients are likely to benefit from particular treatments.´´

´´He has also helped illuminate the biological basis for how acquired mutations drive the transformation of hematopoietic (blood-forming) cells. ´´

´´In addition, as chair of medical oncology at Dana-Farber, Ebert oversees more than 200 faculty members who study the causes of, and develop new therapies for, a range of adult cancers.´´

“Let me recognize you, Dr. Ebert, as an outstanding member of our faculty, an exceptional researcher and a clinician who is most deserving of this great honor,” said HMS Dean George Q. Daley at the celebration.´´

Dean Daley hands crystal bowl to couple
HMS Dean George Q. Daley presents a crystal bowl to professorship namesakes George and Jean Canellos. Image: Gretchen Ertl

´´The professorship’s co-namesake, George Canellos, served as founding chief of medical oncology at Dana-Farber from 1975 to 1995. He is now the William Rosenberg Professor of Medicine, Emeritus, at HMS.´´

“Dr. Canellos, given the sheer number of family members, friends, colleagues and patients who contributed to this professorship, it is evident that you are held in the highest regard,” said Daley.´´

“It is our great honor to have the Canellos name be associated with Harvard Medical School in perpetuity through this professorship,” he added.´´

´´Jean Canellos, a charter member and former president of the Friends of Dana-Farber Cancer Institute, said, “It is a special pleasure that Dr. Ebert will be the first incumbent to the professorship,” adding that she hoped he enjoys being part of the Dana-Farber family as much as she and her husband have.´´

´´Laurie Glimcher, president and CEO of Dana-Farber, director of the Dana-Farber/Harvard Cancer Center and the Richard and Susan Smith Professor of Medicine at HMS, said Dana-Farber is lucky to have Ebert on its faculty and that Canellos is “an oncology luminary and an icon of education.”

´´The professorship was made possible in part by the family of the late Nicola David-Pinedo, a former patient at Dana-Farber, and the Stavros Niarchos Foundation, an international philanthropic organization that provides grants to nonprofits in the areas of arts and culture, education, health and sports, and social welfare.´´

 

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