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The influence of physical activity in the progression of experimental lung cancer in mice
- PMID: 22683274
- DOI: 10.1016/j.prp.2012.04.006
GRUPO_AF1 – GROUP AFA1 – Aerobic Physical Activity – Atividade Física Aeróbia – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto
GRUPO AFAN 1 – GROUP AFAN1 – Anaerobic Physical Activity – Atividade Física Anaeróbia – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto
GRUPO_AF2 – GROUP AFA2 – Aerobic Physical Activity – Atividade Física Aeróbia – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto
GRUPO AFAN 2 – GROUP AFAN 2 – Anaerobic Physical Activity – Atividade Física Anaeróbia – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto
Slides – mestrado – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto
DMBA CARCINOGEN IN EXPERIMENTAL MODELS
Avaliação da influência da atividade física aeróbia e anaeróbia na progressão do câncer de pulmão experimental – Summary – Resumo – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto
Lung cancer is one of the most incident neoplasms in the world, representing the main cause of mortality for cancer. Many epidemiologic studies have suggested that physical activity may reduce the risk of lung cancer, other works evaluate the effectiveness of the use of the physical activity in the suppression, remission and reduction of the recurrence of tumors. The aim of this study was to evaluate the effects of aerobic and anaerobic physical activity in the development and the progression of lung cancer. Lung tumors were induced with a dose of 3mg of urethane/kg, in 67 male Balb – C type mice, divided in three groups: group 1_24 mice treated with urethane and without physical activity; group 2_25 mice with urethane and subjected to aerobic swimming free exercise; group 3_18 mice with urethane, subjected to anaerobic swimming exercise with gradual loading 5-20% of body weight. All the animals were sacrificed after 20 weeks, and lung lesions were analyzed. The median number of lesions (nodules and hyperplasia) was 3.0 for group 1, 2.0 for group 2 and 1.5-3 (p=0.052). When comparing only the presence or absence of lesion, there was a decrease in the number of lesions in group 3 as compared with group 1 (p=0.03) but not in relation to group 2. There were no metastases or other changes in other organs. The anaerobic physical activity, but not aerobic, diminishes the incidence of experimental lung tumors.
Copyright © 2012 Elsevier GmbH. All rights reserved.
A Dutch startup has made Europe’s first functioning Hyperloop system, six years after Elon Musk hinted that he wanted to do the same
- Elon Musk revealed plans for Hyperloop in 2013, a form of transport that entails capsules being propelled through a tube.
- The system could theoretically carry passengers from one destination to another at over 1,000 kilometers per hour and could be a green alternative to short-haul flights.
- According to a press release from tech startup Hardt, the Dutch company has successfully completed Europe’s first Hyperloop tunnel, bringing us one step closer to launching the system.
- Visit Business Insider’s homepage for more stories.
In 2013, Elon Musk revealed his vision for an unprecedented approach to travel: the Hyperloop.
The idea involves capsules being propelled through a tube, sending passengers gliding over 1,000 kilometers per hour, according toScience Alert.
Using a combination of negative pressure and magnetic forces, the Hyperloop is designed to transport passengers at extremely high speeds.
Six years later and the idea has generated a lot of interest, but it’s not just Tesla’s boss exploring alternative and fast means of transport; a number of scientists, institutes, and startups are doing the same — even Richard Branson has plans for his own Hyperloop, the Virgin Hyperloop One.
Now, according to a press release, Dutch tech startup Hardt wants to conquer Europe with its own vision for a Hyperloop and has taken the first steps in implementing Europe’s first tunnel.
A 30-meter long Hyperloop test track has been put into operation
According to the startup, the tunnel section, which is only 30 meters long and was built in Delft in the Netherlands, now comprises all the core elements necessary for a functioning Hyperloop system.
This means that, among other things, transportation of passenger modules can be tested here, as well as vacuum generation and magnetic levitation (Maglev).
By working on this futuristic method of transportation, Hardt is also looking at unique technology called lane switch technology.
This technology will allow passenger modules — which move in tubes — to switch from one lane to another without reducing their speed and without the need for any extra components or moving parts. This would also allow them to alter their routes.
Hardt is planning an even larger Hyperloop network for Europe
In the long term, Hardt is planning an extensive network in Europe at an ambitious total length of 10,000 kilometers.
A more climate-friendly alternative to air travel, the Hyperloop route network will initially connect major cities with one another and be.
By 2021, a research and development center with a three-kilometer-long test tunnel dubbed the European Hyperloop Center will also be built.
“The next phase is to realize a high-speed test facility, acquiring the right partnerships to raise the right amount of investment required for that,” co-founder of Hardt Tim Houter told CNBC.
Hardt is hoping its first commercial Hyperloop line will be in operation by 2028, but discussion over the 450-kilometer route between Frankfurt and Amsterdam is apparently still underway.
North Holland’s government recently told De Telegraaf that it would work closely with Hardt to build a Hyperloop tube between Schiphol’s and Frankfurt’s airports.
In addition to the possibility that the route could take less than half an hour, the train is a climate-friendly alternative to short-haul flights, a spokeswoman for the government told De Telegraaf.Read the original article on Business Insider Deutschland.This post originally appeared on Business Insider Deutschland and has been translated from German.Copyright 2019. Follow Business Insider Deutschland on Twitter.
SEE ALSO: Richard Branson just unveiled his vision for Virgin Hyperloop One — and it looks straight out of a sci-fi film
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