Do the downloads!! Share!! The diffusion of very important information and knowledge is essential for the world progress always!! Thanks!!
- – > Mestrado – Dissertation – Tabelas, Figuras e Gráficos – Tables, Figures and Graphics – ´´My´´ Dissertation @ #Innovation #energy #life #health #Countries #Time #Researches #Reference #Graphics #Ages #Age #Mice #People #Person #Mouse #Genetics #PersonalizedMedicine #Diagnosis #Prognosis #Treatment #Disease #UnknownDiseases #Future #VeryEfficientDrugs #VeryEfficientVaccines #VeryEfficientTherapeuticalSubstances #Tests #Laboratories #Investments #Details #HumanLongevity #DNA #Cell #Memory #Physiology #Nanomedicine #Nanotechnology #Biochemistry #NewMedicalDevices #GeneticEngineering #Internet #History #Science #World
The influence of physical activity in the progression of experimental lung cancer in mice
- PMID: 22683274
- DOI: 10.1016/j.prp.2012.04.006
GRUPO_AF1 – GROUP AFA1 – Aerobic Physical Activity – Atividade Física Aeróbia – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto
GRUPO AFAN 1 – GROUP AFAN1 – Anaerobic Physical Activity – Atividade Física Anaeróbia – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto
GRUPO_AF2 – GROUP AFA2 – Aerobic Physical Activity – Atividade Física Aeróbia – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto
GRUPO AFAN 2 – GROUP AFAN 2 – Anaerobic Physical Activity – Atividade Física Anaeróbia – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto
Slides – mestrado – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto
DMBA CARCINOGEN IN EXPERIMENTAL MODELS
Avaliação da influência da atividade física aeróbia e anaeróbia na progressão do câncer de pulmão experimental – Summary – Resumo – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto
Lung cancer is one of the most incident neoplasms in the world, representing the main cause of mortality for cancer. Many epidemiologic studies have suggested that physical activity may reduce the risk of lung cancer, other works evaluate the effectiveness of the use of the physical activity in the suppression, remission and reduction of the recurrence of tumors. The aim of this study was to evaluate the effects of aerobic and anaerobic physical activity in the development and the progression of lung cancer. Lung tumors were induced with a dose of 3mg of urethane/kg, in 67 male Balb – C type mice, divided in three groups: group 1_24 mice treated with urethane and without physical activity; group 2_25 mice with urethane and subjected to aerobic swimming free exercise; group 3_18 mice with urethane, subjected to anaerobic swimming exercise with gradual loading 5-20% of body weight. All the animals were sacrificed after 20 weeks, and lung lesions were analyzed. The median number of lesions (nodules and hyperplasia) was 3.0 for group 1, 2.0 for group 2 and 1.5-3 (p=0.052). When comparing only the presence or absence of lesion, there was a decrease in the number of lesions in group 3 as compared with group 1 (p=0.03) but not in relation to group 2. There were no metastases or other changes in other organs. The anaerobic physical activity, but not aerobic, diminishes the incidence of experimental lung tumors.
Copyright © 2012 Elsevier GmbH. All rights reserved.
´´A computer’s memory can be viewed as a list of cells into which numbers can be placed or read. Each cell has a numbered “address” and can store a single number. The computer can be instructed to “put the number 123 into the cell numbered 1357” or to “add the number that is in cell 1357 to the number that is in cell 2468 and put the answer into cell 1595.” The information stored in memory may represent practically anything. Letters, numbers, even computer instructions can be placed into memory with equal ease.´´
http://www.google.com http://www.youtube.com https://charcot-marie-toothnews.com/2019/11/15/crispr-based-treatment-improves-nerve-functionig-cmt1a-mice-study/?fbclid=IwAR1UNJDxbFMEaLvUOSTKxUBjqWeYhjbojI16ZuWvtbLB1vhT5D5DxtHrr4A
http://www.wordpress.com http://www.science1984.wordpress.com http://www.google.com http://www.youtube.com http://www.yahoo.com http://www.gmail.com https://www.internetsociety.org/ http://www.harvard.edu
- Disrupt Berlin 2019
- Extra Crunch
Microsoft uses AI to diagnose cervical cancer faster in India
More women in India die from cervical cancer than in any other country. This preventable disease kills around 67,000 women in India every year, more than 25% of the 260,000 deaths worldwide.
Effective screening and early detection can help reduce its incidence, but part of the challenge — and there are several parts — today is that the testing process to detect the onset of the disease is unbearably time-consuming.
This is because the existing methodology that cytopathologists use is time consuming to begin with, but also because there are very few of them in the nation. Could AI speed this up?
At SRL Diagnostics, the largest chain to offer diagnostic services in pathology and radiology in India, we are getting an early look of this. Last year, Microsoft partnered with SRL Diagnostics to co-create an AI Network for Pathology to ease the burden of cytopathologists and histopathologists.
SRL Diagnostics receives more than 100,000 Pap smear samples every year. About 98% of these samples are typically normal and only the remaining 2% samples require intervention. “We were looking for ways to ensure our cytopathologists were able to find those 2% abnormal samples faster,” explained Dr. Arnab Roy, Technical Lead for New Initiatives & Knowledge Management at SRL Diagnostics.
Cytopathologists at SRL Diagnostics studied digitally scanned versions of Whole Slide Imaging (WSI) slides, each comprising about 300-400 cells, manually and marked their observations, which were used as training data for Cervical Cancer Image Detection API.
A digitally scanned version of a Whole Slide Imaging (WSI) slide, which is used to train the AI model
Then there was the challenge of subjectivity. “Different cytopathologists examine different elements in a smear slide in a unique manner even if the overall diagnosis is the same. This is the subjectivity element in the whole process, which many a time is linked to the experience of the expert,” reveals Dr. Roy.
Manish Gupta, Principal Applied Researcher at Microsoft Azure Global Engineering, who worked closely with the team at SRL Diagnostics, said the idea was to create an AI algorithm that could identify areas that everybody was looking at and “create a consensus on the areas assessed.”
Cytopathologists across multiple labs and locations annotated thousands of tile images of cervical smear. They created discordant and concordant notes on each sample image.
“The images for which annotations were found to be discordant — that is if they were viewed differently by three team members — were sent to senior cytopathologists for final analysis,” Microsoft wrote in a blog post.
This week, the two revealed that their collaboration has started to show results. SRL Diagnostics has started an internal preview to use Cervical Cancer Image Detection API. The Cervical Cancer Image Detection API, which runs on Microsoft’s Azure, can quickly screen liquid-based cytology slide images for detection of cervical cancer in the early stages and return insights to pathologists in labs, the two said.
The AI model can now differentiate between normal and abnormal smear slides with accuracy and is currently under validation in labs for a period of three to six months. It can also classify smear slides based on the seven-subtypes of cervical cytopathological scale, the two wrote in a blog post.
During the internal preview period, the exercise will use more than half-a-million anonymized digital tile images. Following internal validation, the API will be previewed in external cervical cancer diagnostic workflows, including hospitals and other diagnostic centers.
“Cytopathologists now have to review fewer areas, 20 as of now, on a whole slide liquid-based cytology image and validate the positive cases thus bringing in greater efficiency and speeding up the initial screening process,” Microsoft wrote.
“The API has the potential of increasing the productivity of a cytopathology section by about four times. In a future scenario of automated slide preparation with assistance from AI, cytopathologists can do a job in two hours what would earlier take about eight hours!” Dr. Roy said.
SRL Diagnostics-Microsoft consortium said they are hopeful their APIs could find application in other fields of pathology such as diagnosis of kidney pathologies and in oral, pancreatic and liver cancers. The consortium also aims to expand its reach with tie-ups with private players and governments and expand the reach of the model even in remote geographies where the availability of histopathologists is a challenge.
The announcement this week is the latest example of Microsoft’s ongoing research work in India. The world’s second most populous nation has become a test bed for many American technology companies to build new products and services that solve local challenges as they look for their next billion users worldwide.
Last week, Microsoft announced its AI project was helping improve the way driving tests are conducted in India. The company has unveiled a score of tools for the Indian market in the last two years. Microsoft has previously developed tools to help farmers in India increase their crop yields and worked with hospitals to prevent avoidable blindness. Last year, the company partnered with Apollo Hospitals to create an AI-powered API customized to predict risk of heart diseases in India.
Also last year, the company also worked with cricket legend Anil Kumble to develop a tracking device that helps youngsters analyze their batting performance. Microsoft has also tied up with insurance firm ICICI Lombard to help it process customers’ repair claims and renew lapsed policies using an AI system.Conversation
BerlinDec 11 – 12Save €500 Now
Sign up for Newsletters
See all newsletters(opens in a new window)The Daily CrunchWeek in ReviewStartups WeeklyThe StationExtra Crunch RoundupEvent UpdatesSponsorship InsiderCrunchbase DailyEmailSubscribe(opens in a new window)(opens in a new window)(opens in a new window)(opens in a new window)Copy
Manish Singh10:00 am -03 • November 9, 2019
More women in India die from cervical cancer than in any other country. This preventable disease kills around 67,000 women in India every year, more than 25% of the 260,000 deaths worldwide. Effect…
We talk a lot about startup ecosystems around these parts, and for good reason. Strong ecosystems…Danny Crichton7:16 pm -03 • November 9, 2019
Lucas Matney6:00 pm -03 • November 9, 2019
Hey everyone. Thank you for welcoming me into you inbox yet again. I got some awesome responses to the #DeleteLinkedIn newsletter last week, a few dozen emails (some of them angry) and plenty of tw…
Zack Whittaker2:24 pm -03 • November 9, 2019
Two security researchers have been crowned the top hackers in this year’s Pwn2Own hacking contest after developing and testing several high profile exploits, including an attack against an Am…
Original Content podcast: Apple’s star-studded ‘Morning Show’ gets off to a bumpy-but-promising start
We weren’t sure what to expect from the launch of Apple’s new subscription streaming service. There were reports that the company was committed to staying family friendly, rather than exploring the…
Darrell Etherington11:31 am -03 • November 9, 2019
MIT’s Biomimetics Robotics department took a whole herd of its new ‘mini cheetah’ robots out for a group demonstration on campus recently – and the result is an adorable, impressi…
Sarah Perez11:00 am -03 • November 9, 2019
Welcome back to This Week in Apps, the Extra Crunch series that recaps the latest OS news, the applications they support, and the money that flows through it all. What are the developers talking ab…
Kate Clark10:00 am -03 • November 9, 2019
In this week’s newsletter: Airbnb’s new safety measures, Coveo’s unicorn round and the TechCrunch Disrupt Berlin agenda.
Sarah Perez12:03 am -03 • November 9, 2019
The Roku remote is coming to your wrist. The company announced today the launch of an Apple Watch app that lets you control your Roku device, including Roku media players and select Roku TVs, with …
Manish Singh11:46 pm -03 • November 8, 2019
36Kr, a Chinese news and data website that tracks startups, fell 10% in its Nasdaq debut on Friday. The disappointing debut followed 36Kr’s decision to slash the size of its offering from 3.6…
Josh Constine9:25 pm -03 • November 8, 2019
“We will make decisions that hurt the business if they help people’s well-being and health” says Instagram’s CEO Adam Mosseri. To that end, next week Instagram will expand i…
Hugh Harsono8:13 pm -03 • November 8, 2019
A move to East Kalimantan would allow for further development in the startup industry, with a focus on ecommerce and sustainability-focused enterprises.
Chris Cox’s motivational speeches were at the heart of Facebook’s new employee orient…Josh Constine7:08 pm -03 • November 8, 2019
Veanne Cao7:00 pm -03 • November 8, 2019
Joshua Luber runs a sneaker empire valued at more than $1 billion, but he thinks they’re just now scratching the surface. The consumer marketplace recently expanded to include a fifth category (col…
The crowded landscape of programs teaching non-technical people to become software developers has…Eric Peckham6:55 pm -03 • November 8, 2019
Leslie Hitchcock6:12 pm -03 • November 8, 2019
We won’t bury the lead on this news, startup fans. We’re giving all you professional procrastinators and time-delayed decision makers an extra week to pull yourselves together and score early-bird …
Sarah Perez6:05 pm -03 • November 8, 2019
This July, Facebook announced a new division called NPE Team which would build experimental consumer-facing apps, allowing the company to try out new ideas and features to see how people would reac…
Anthony Ha5:32 pm -03 • November 8, 2019
The Daily Crunch is TechCrunch’s roundup of our biggest and most important stories. If you’d like to get this delivered to your inbox every day at around 9am Pacific, you can subscribe …
Devin Coldewey5:23 pm -03 • November 8, 2019
Official word has come down from federal authorities on one potential cause of the mystery illness affecting vape users: Vitamin E acetate, a chemical found in some vaping products that has been de…
Aaron Bartnick4:16 pm -03 • November 8, 2019
Jack Dorsey made a wise choice for both his bottom line and his country. Facebook and Google would do well to follow his lead.
- Do Not Sell My Personal Information
- About Our Ads
- Code of Conduct
- Terms of Service