WHAT’S A FEW ZEROS BETWEEN FRIENDS? 2020 is the year of the $1 trillion space economy – By Tim Fernholz December 30, 2019 @ Ultimate Guide to write Perfect Research Proposal & Editing: Things they don’t tell you about what journal editors want @ How to get a paper published in a high impact journal? @ Top 100 Impact Factor Journals of Science Indexed in ISI Web of Science (JCR Science Citation Index, 2016) @ ´´The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index that reflects the yearly average number of citations that articles published in the last two years in a given journal received. It is frequently used as a proxy for the relative importance of a journal within its field; journals with higher impact factors are often deemed to be more important than those with lower ones.´´The impact factor was devised by Eugene Garfield, the founder of the Institute for Scientific Information (ISI). Impact factors are calculated yearly starting from 1975 for journals listed in the Journal Citation Reports (JCR). ISI was acquired by Thomson Scientific & Healthcare in 1992,[1] and became known as Thomson ISI. In 2018, Thomson ISI was sold to Onex Corporation and Baring Private Equity Asia.[2] They founded a new corporation, Clarivate, which is now the publisher of the JCR.[3]´´

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Pathol Res Pract. 2012 Jul 15;208(7):377-81. doi: 10.1016/j.prp.2012.04.006. Epub 2012 Jun 8.

The influence of physical activity in the progression of experimental lung cancer in mice

Renato Batista Paceli 1Rodrigo Nunes CalCarlos Henrique Ferreira dos SantosJosé Antonio CordeiroCassiano Merussi NeivaKazuo Kawano NagaminePatrícia Maluf Cury


Impact_Fator-wise_Top100Science_Journals

GRUPO_AF1 – GROUP AFA1 – Aerobic Physical Activity – Atividade Física Aeróbia – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto

GRUPO AFAN 1 – GROUP AFAN1 – Anaerobic Physical Activity – Atividade Física Anaeróbia – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto

GRUPO_AF2 – GROUP AFA2 – Aerobic Physical Activity – Atividade Física Aeróbia – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto

GRUPO AFAN 2 – GROUP AFAN 2 – Anaerobic Physical Activity – Atividade Física Anaeróbia – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto

Slides – mestrado – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto

CARCINÓGENO DMBA EM MODELOS EXPERIMENTAIS

DMBA CARCINOGEN IN EXPERIMENTAL MODELS

Avaliação da influência da atividade física aeróbia e anaeróbia na progressão do câncer de pulmão experimental – Summary – Resumo – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto

https://pubmed.ncbi.nlm.nih.gov/22683274/

Abstract

Lung cancer is one of the most incident neoplasms in the world, representing the main cause of mortality for cancer. Many epidemiologic studies have suggested that physical activity may reduce the risk of lung cancer, other works evaluate the effectiveness of the use of the physical activity in the suppression, remission and reduction of the recurrence of tumors. The aim of this study was to evaluate the effects of aerobic and anaerobic physical activity in the development and the progression of lung cancer. Lung tumors were induced with a dose of 3mg of urethane/kg, in 67 male Balb – C type mice, divided in three groups: group 1_24 mice treated with urethane and without physical activity; group 2_25 mice with urethane and subjected to aerobic swimming free exercise; group 3_18 mice with urethane, subjected to anaerobic swimming exercise with gradual loading 5-20% of body weight. All the animals were sacrificed after 20 weeks, and lung lesions were analyzed. The median number of lesions (nodules and hyperplasia) was 3.0 for group 1, 2.0 for group 2 and 1.5-3 (p=0.052). When comparing only the presence or absence of lesion, there was a decrease in the number of lesions in group 3 as compared with group 1 (p=0.03) but not in relation to group 2. There were no metastases or other changes in other organs. The anaerobic physical activity, but not aerobic, diminishes the incidence of experimental lung tumors.

´´We propose to change the default P-value threshold for statistical significance from 0.05 to 0.005 for claims of new discoveries.´´ https://www.nature.com/articles/s41562-017-0189-z Published:  Daniel J. Benjamin, James O. Berger, […]Valen E. Johnson Nature Human Behaviour volume 2, pages6–10 (2018)

Um mundo além de p < 0,05 « Sandra Merlo – Fonoaudiologia da Fluência

´´My´´ Monografia – Monograph – Induction of benznidazole resistance in human Trypanosoma cruzi isolates – Indução de resistência ao benzonidazol em isolados humanos de Trypanosoma cruzi – UFTM – Federal University of Triangulo Mineiro – Uberaba 

Avaliação da influência da atividade física aeróbia e anaeróbia na progressão do câncer de pulmão experimental – Summary – Resumo

Article – ´´My´´ dissertation – Faculty of Medicine of Sao Jose do Rio Preto

Feedback positivo de pessoas sobre minha dissertação pelo Messenger – Facebook. Positive feedback of people about my dissertation, blog and YouTube channel by Facebook – Messenger. Year – Ano: 2018

LISTA DE NOMES DE PESSOAS QUE ME DERAM FEEDBACK POSITIVO SOBRE A LISTA DE EMAILS QUE FIZ EM 2015 (PROJETO) – PEOPLE´S NAMES (POSITIVE FEEDBACK ABOUT THE EMAIL LIST I DID IN 2015) – E-MAIL LIST – LISTA DE E-MAILS – PROJECT – PESQUISA -RESEARCH

My suggestion of a very important Project…

Apostila – Pubmed

A Psicossomática Psicanalítica – Faculty of Medicine of Sao Jose do Rio Preto

ÁCIDO HIALURÔNICO – HIALURONIC ACID – Faculty of Medicine of Sao Jose do Rio Preto

Slides – Mestrado final – ´´My´´ dissertation – Faculty of Medicine of Sao Jose do Rio Preto

Avaliação da influência da atividade física aeróbia e anaeróbia na progressão do câncer de pulmão experimental – Summary – Resumo

O Homem como Sujeito da Realidade da Saúde – Redação – Faculty of Medicine of Sao Jose do Rio Preto

Aula_Resultados – Results – FAMERP – Faculty of Medicine of Sao Jose do Rio Preto

As credenciais da ciência – The credentials of Science – Faculty of Medicine of Sao Jose do Rio Preto BaixarFrases que digitei – Phrases I typed

Frases que digitei – Tecnologia – Informations about blog I did

Keynote-The-Future-of-Space-Exploration(1)

2019-01-hormone-alzheimer(1)

mojap-02-00034

ajpheart.00349.2013

aging – animal models

Nanomedicine an evolving research (Opinion article I typed)

journal-of-nanomedicine–nanotechnology-flyer

Will you embrace AI fast enough

MICROBIOLOGIA – MICROBIOLOGY – Faculty of Medicine of Sao Jose do Rio Preto

Genes e Epilepsia – Genes and epilepsy – Faculty of Medicine of Sao Jose do Rio Preto

Dr.A.M.S

Flav_R03

BIOGRAFIA – BIOGRAPH – DR. DOMINGO MARCOLINO BRAILE

p-Value – Valor de p

european-respiratory-society

redefine-statistical-significance

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SpaceX founder and chief executive Elon Musk speaks after announcing Japanese billionaire Yusaku Maezawa as the first private passenger on a trip around the moon, Monday, Sept. 17, 2018, in Hawthorne, Calif.
Going up.

WHAT’S A FEW ZEROS BETWEEN FRIENDS?

2020 is the year of the $1 trillion space economy

By Tim FernholzDecember 30, 2019

The first time I can find “space economy” and “trillion dollars” in the same sentence is in 1984, when then-congressman Robert Walker told the Associated Press that a space station in low-Earth orbit could “lead to a half-trillion-dollar economy in space by the turn of the century.”

Some 35 years later, we’ve fallen short of the mark. The best estimates of the money made from space—which these days mostly come from building and operating rockets and satellites, and using them to provide services back on Earth—is about $400 billion. To be fair to Walker, now a lobbyist who served on US president Donald Trump’s NASA transition team, the space station under discussion didn’t begin operations until 2000.

The turn of the century was a hard time for the space economy, as tech bubble-driven dreams of internet satellites and venture-backed moon missions fizzled out alongside the stock market.

But a lot has changed since then, and the dream of a trillion dollar space economy is now cited by everyone from government officials and space entrepreneurs to Fortune 500 executives and Wall Street investment banks. Analysts at Morgan Stanley and Goldman Sachs have predicted that economic activity in space will become a multi-trillion-dollar market in the coming decades, and the US Bureau of Economic Analysis has launched a new initiative to measure it.

The trends driving this optimism are the same ones driving the tech economy writ large: The increasing power and miniaturization of transistors, batteries and solar panels, generated in part by the smartphone revolution; the convergence of telecommunications, broadcast media, commerce and nearly everything else into “the internet”; and, naturally, geopolitical tensions that still have governments spending on space and, increasingly, hiring private companies.

What does this look like in practice in 2020?

The rise of the mega-constellations

Elon Musk’s SpaceX plans to launch its fifth rocket full of proprietary internet satellites in January. That will raise the total number of satellites in the company’s Starlink constellation to about 300, well on the way to the roughly 480 the company’s executives say they’ll need to begin offering broadband internet access to customers on Earth. How exactly that will happen—as a direct to consumer product or as a partnership with terrestrial telecom firms—remains to be seen, but Musk and his team are confident that if they can build low-latency connectivity, the buyers will come.

SpaceX is hardly the only group making this bet: OneWeb, Telesat and Amazon are also investing billions in networks of thousands of internet connectivity satellites. Apple is also reportedly chasing the dream of space connectivity.

To be sure, this isn’t the first time satellite internet in space on a mass scale has been tried—Bill Gates notably invested in a failed effort called Teledesic in the 1990s. What’s different is that all the components—satellites and the rockets that launch them—are an order of magnitude cheaper, the latter thanks mostly to the efforts of Musk to drive down the cost of launch. And meanwhile, the demand for internet access isn’t a novelty, but ravenous and central to the economy.

Most of the money made in space is on the back of satellite-provided service, so these efforts are likely to meaningfully increase the space economy. The huge increase in satellites (there are about 2,300 operational satellites in space right now) will bring costs as well as benefits, with astronomers worried about interference and everyone fretting about managing all that traffic and dodging space debris. Yet that is likely to spur investment in new satellite servicing businesses that seek to keep low-Earth orbit clean and efficient.

The rise of the mini-constellations

Venture capitalists have also been throwing millions of dollars at small satellite companies with big dreams. Planet, Hawkeye360, Spire, Capella Space, BlackSky and Swarm are just some of the firms who have raised cash, launched satellites, and are planning for a big 2020. Their business models vary, from tracking radio signals and gathering radar data to imaging every inch of the Earth to communicating with internet-of-things devices. But they all depend on the falling cost of building and operating spacecraft to enable their work.

In response to the growing corps of companies operating small satellites, we’ve seen a growing number of firms building rockets fit for the task. Rocket Lab has been the most successful, but Virgin Orbit promises to begin operations in 2020, and Relativity Space remains on track for a maiden launch in 2021.

New options for human spaceflight

It’s been a long year of one-step-forward, one-step-back for the commercial crew program, NASA’s efforts to develop a private space transportation service with Boeing and SpaceX. But both companies are now in the final stretch, with orbital flights of their vehicles under their belts. Sometime in 2020, we can expect them to begin regular service to the International Space Station. NASA officials expect that to increase the amount of research done on the station, a big plus for the space economy.

The companies will also have the green light to start bringing up paid passengers, whether wealthy tourists or corporate researchers. While uncertain, that promises new revenues and new opportunities for private-sector activity in low-Earth orbit.

Closer to the ground, we can still look forward to space tourism. Virgin Galactic went public this year in a reverse merger, and now Richard Branson’s space tourism firm says it has the cash to begin flying regular tourist trips to the edge of space sometime in 2020 for a cool $250,000 a pop. Blue Origin, Jeff Bezos’ space firm, said it would fly people on its New Shepard suborbital rocket this year, but with a week left, has not—so perhaps 2020 will be the year the company demonstrates its human spaceflight chops.

NASA’s public-private partnerships

NASA’s biggest space projects, particularly its plans to return humans to the moon, have had a tough year, with allegations of mismanagement and problems ranging from delayed hardware to muddled strategy. Space visionaries see that return to the moon—and access to the water ice discovered there—as key to the grandest visions of a future space economy, with thousands of people living and working in Earth orbit. For now, though, it’s not clear whether the US government can resolve the conflicts between its goals for space exploration and its willingness to change the way NASA does business enough to create a sustainable presence on the moon.

In the meantime, NASA is investing in smaller but perhaps more meaningful efforts to bolster the space economy. From the lunar side, it is hiring private companies to build spacecraft, landers and rovers that will carry scientific instruments to the moon. The space agency hopes that, as with its partnerships to fly cargo and crew to the International Space Station, this strategy will deliver more scientific bang for the taxpayer buck. From an economic perspective, the program is likely to bolster the know-how of private companies when it comes to operating on the moon, iterating towards that grand vision.

There’s also forward movement in low-Earth orbit, where the International Space Station has been opened up to more commercial activity, part of NASA’s hope to start sharing the costs of humanity’s space outpost more broadly.

Space Force

This year marked the creation of the Space Force, a branch of the US military dedicated to space as a warfighting domain. Immediate change will be little more than existing US Air Force personnel changing their uniforms and titles, but the move spells a real shift in how the US military treats space. Right now, space exists mostly to aid and abet the other services in projecting power overseas, providing reconnaissance, communications, guidance and navigation.

Space Force, at heart, is about creating a bureaucratic and political constituency for thinking bigger in orbit—and investing in new space sensors to track enemy missiles, spacecraft that can defend themselves (and attack others), even crewed military habitats. All that means more money for private companies in space, with half-a-dozen defense agencies already pumping millions into space start-ups building everything from radar networks to high-tech materials.

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