Links about ´´My´´ Dissertation, ´´My´´ Monograph And Animal Models for Human Diseases like Cardiovascular Diseases @ EDITORIAL – 20 MARCH 2019 – ´´It’s time to talk about ditching statistical significance – Looking beyond a much used and abused measure would make science harder, but better.´´É hora de falar sobre a redução da significância estatística – Olhar além de uma medida muito usada e abusada tornaria a ciência mais difícil, mas melhor.´´ Nature 567, 283 (2019) doi: 10.1038/d41586-019-00874-8 @ Comments by Facebook about this Blog & Comments I did Today in Facebook Lives @ WHAT DOES STATISTICALLY SIGNIFICANT MEAN? by Jeff Sauro, PhD | October 21, 2014 ´´If researchers do discard statistical significance, what should they do instead? They can start by educating themselves about statistical misconceptions. Most important will be the courage to consider uncertainty from multiple angles in every study.´´ @ WORLD’S FASTEST SUPERCOMPUTER FINDS 77 POTENTIAL COVID-19 TREATMENTS – IT’S NOT A CURE, BUT IT’S A STEP IN THE RIGHT DIRECTION. @ Confirmed Coronavirus Cases Are Growing Faster In The United States Than Any Other Country In The World @ AUGMENTING YOUR IMMUNITY: FIGHTING COVID-19 @ Wikipedia Links about Disease, Science, Research and Statistics @ OTHER VERY IMPORTANT INFORMATION OF THE WORLD, LIKE LINKS, WEBSITES AND IMAGES

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´´The world people need to have very efficient researches and projects resulting in very innovative drugs, vaccines, therapeutical substances, medical devices and other technologies according to the age, the genetics and medical records of the person. So, the treatment, diagnosis and prognosis will be very efficient and better, of course´´. Rodrigo Nunes Cal

https://science1984.wordpress.com/2021/08/14/do-the-downloads-of-very-important-detailed-and-innovative-data-of-the-world-about-my-dissertation-like-the-graphics-i-did-about-the-variations-of-weights-of-all-mice-control/

Mestrado – Dissertation – Tabelas, Figuras e Gráficos – Tables, Figures and Graphics


Impact_Fator-wise_Top100Science_Journals

GRUPO_AF1

GRUPO_AF2

GRUPO AFAN 1

GRUPO AFAN 2

Slides – mestrado

CARCINÓGENO DMBA EM MODELOS EXPERIMENTAIS

Avaliação da influência da atividade física aeróbia e anaeróbia na progressão do câncer de pulmão experimental – Summary – Resumo

  • I DID VERY INTERESTING, INNOVATIVE, IMPORTANT AND DETAILED GRAPHICS ABOUT VARIATIONS OF ALL MICE WEIGHTS OF DIFFERENT AGES DURING ALL EXPERIMENTAL TIME OF ´´MY´´ DISSERTATION. THEY´RE AVAILABLE IN THIS BLOG AND ARE VERY IMPORTANT TO THE SCIENTIFIC COMMUNITY!! THE DIFFUSION OF RELEVANT KNOWLEDGE IS ALWAYS ESSENTIAL FOR A COUNTRY PROGRESS. NEW SCIENTIFIC DISCOVERIES NEED TO EMERGE URGENTLY !! BELOW YOU CAN DO DOWNLOAD OF THESE GRAPHICS AND OTHER DOCUMENTS RELATED TO SCIENCE, TECHNOLOGY AND INNOVATION. SO, SHARE THESE GRAPHICS AND OTHER DOCUMENTS TO OTHER PEOPLE KNOW ABOUT IT AND PERHAPS USE THEM AS AN EXCELLENT REFERENCE IN THE SCIENTIFIC RESEARCHES. @ PERSON – PEOPLE – ANALYSIS – TIME – DATA – GRAPHICS – RESEARCHES – VISION – READING – SPEAKING – LISTENING – INFORMATION – KNOWLEDGE – INTENTIONS – INNOVATIONS – CHANGES – DATA INTERPRETATIONS – NEW INNOVATIONS – INTERNET – BOOKS – GRAPHICS INTERPRETATIONS – GRAPHICS COMPARISONS – INFLUENCES – TIME – SUBSTANCES – DRUGS – VACCINES – NEW MEDICAL DEVICES – WORLD HISTORY – NEW TECHNOLOGIES – HUMAN ENERGY – WORK – NEW SCIENTIFIC DISCOVERIES – SCIENCE – GRAPHICS ANALYSIS – AGES – AGE – GENETICS – PHYSIOLOGY – MIND – MOLECULAR BIOLOGY – STATISTICS – BIOSTATISTICS – HUMAN LONGEVITY

Mestrado – ´´My´´ Dissertation – Tabelas, Figuras e Gráficos – Tables, Figures and Graphics


Impact_Fator-wise_Top100Sciene_Journals

GRUPO_AF1 – ´´my´´ dissertation

GRUPO_AF2 – ´´my´´ dissertation

GRUPO AFAN 1 – ´´my´´ dissertation

GRUPO AFAN 2 – ´´my´´ dissertation

Slides – mestrado – ´´my´´ dissertation

CARCINÓGENO DMBA EM MODELOS EXPERIMENTAIS

Avaliação da influência da atividade física aeróbia e anaeróbia na progressão do câncer de pulmão experimental – Summary – Resumo – ´´my´´ dissertation

Positive Feedbacks by Facebook and Twitter about this Blog, like the very important, innovative and detailed graphics I did about variations of all mice weights (Control and Study Groups) of different ages during all experimental time of ´´my´´ dissertation. Note: I have received positive feedbacks about this Blog by LinkedIn, E-mails and Instagram too. @ Internet invitations I received by direct messages to participate in very important science events worldwide in less than 1 year because I participated of great researches in Brazil and other informations @ Links & The next step in nanotechnology | George Tulevski & Animated Nanomedicine movie @ Nanotechnology Animation & Powering Nanorobots & The World’s Smallest Robots: Rise of the Nanomachines & Building Medical Robots, Bacteria sized: Bradley Nelson at TEDxZurich @ Mind-controlled Machines: Jose del R. Millan at TEDxZurich & The present and future of brain-computer interfaces: Avi Goldberg at TEDxAsheville & Future of human/computer interface: Paul McAvinney at TEDxGreenville 2014 @ Bio-interfaced nanoengineering: human-machine interfaces | Hong Yeo | TEDxVCU @ Very important images, websites, social networks and links – https://science1984.wordpress.com/2019/03/17/feedbacks-on-facebook-related-to-researches-i-participated-in-brazil-for-example-the-graphics-i-did-about-variations-of-all-mice-weights-control-and-study-groups-of-different-ages-during-all-exper/

CARCINÓGENO DMBA EM MODELOS EXPERIMENTAIS

monografia – ´´my´´ monograph

Feedback positivo de pessoas sobre minha dissertação pelo Messenger – Facebook. Positive feedback of people about my dissertation, blog and YouTube channel by Facebook – Messenger. Ano – Year: 2018

My suggestion of a very important Project…

rodrigonunescal_dissertation

Apostila – Pubmed

LISTA DE NOMES – PEOPLE´S NAMES – E-MAIL LIST – LISTA DE E-MAILS

A Psicossomática Psicanalítica

O Homem como Sujeito da Realidade da Saúde – Redação

ÁCIDO HIALURONICO

As credenciais da ciência (1)

Aula_Resultados – Results

Frases que digitei – Phrases I typed

Nanomedicina – Texto que escrevi. Nanomedicine – Text I typed(1)

Nanomedicine123(2)57

Genes e Epilepsia

MÉTODOS DE DOSAGEM DO ÁCIDO HIALURÔNICO

microbiologia-famerp – Copia

Impact_Fator-wise_Top100Sciene_Journals

Positive feedback of people about my dissertation, blog and YouTube channel by Messenger (Facebook). Feedback positivo de pessoas sobre minha dissertação, blog e canal do YouTube pelo Facebook (Messenger) Year / Ano: 2018 – positive-feedback-of-people-about-my-dissertation-blog-and-youtube-channel-by-facebook-messenger-ano-year-2018

http://www.google.com http://www.gmail.com http://www.yahoo.com http://www.forbes.com http://www.facebook.com http://www.twitter.com http://www.linkedin.com http://www.youtube.com http://www.cnn.com http://www.bbc.com http://www.usa.gov http://www.instagram.com http://www.wikipedia.org http://www.wordpress.com http://www.harvard.edu http://www.mit.edu

http://www.apple.com http://www.nobelprize.org http://www.nasa.gov http://www.microsoft.com http://www.amazon.com http://www.alibaba.com http://www.stanford.edu http://www.ucla.edu http://www.michigan.edu http://www.caltech.edu http://www.yale.edu http://www.columbia.edu http://www.duke.edu http://www.famerp.br http://www.ita.br http://www.embraer.com

http://www.unicamp.br http://www.twitter.com/CalZole http://www.cornell.edu http://www.uftm.edu.br/

https://www.indispensablesoma.info/who-is-marios-kyriazis​

https://www.indispensablesoma.info/general-facts

My Facebook Page: http://www.facebook.com/scientificblog

https://www.facebook.com/marios.kyriazis/

https://www.visitcyprus.com/index.php/ru/news/195-kyriazis-the-museum-the-man-and-the-medicine

https://www.linkedin.com/pulse/my-interview-man-year-scientist-2017-marios-kyriazis/

Biogerentology.2017 Aug;18(4):711-715. doi: 10.1007/s10522-017-9680-1. Epub 2017 Feb 9.

Biological ageing and clinical consequences of modern technology

Positive Feedbacks by Facebook and Twitter about this Blog, like the very important, innovative and detailed graphics I did about variations of all mice weights (Control and Study Groups) of different ages during all experimental time of ´´my´´ dissertation. Note: I have received positive feedbacks about this Blog by LinkedIn, E-mails and Instagram too. @ Internet invitations I received by direct messages to participate in very important science events worldwide in less than 1 year because I participated of great researches in Brazil and other informations @ Links & The next step in nanotechnology | George Tulevski & Animated Nanomedicine movie @ Nanotechnology Animation & Powering Nanorobots & The World’s Smallest Robots: Rise of the Nanomachines & Building Medical Robots, Bacteria sized: Bradley Nelson at TEDxZurich @ Mind-controlled Machines: Jose del R. Millan at TEDxZurich & The present and future of brain-computer interfaces: Avi Goldberg at TEDxAsheville & Future of human/computer interface: Paul McAvinney at TEDxGreenville 2014 @ Bio-interfaced nanoengineering: human-machine interfaces | Hong Yeo | TEDxVCU @ Very important images, websites, social networks and links – https://science1984.wordpress.com/2019/03/17/feedbacks-on-facebook-related-to-researches-i-participated-in-brazil-for-example-the-graphics-i-did-about-variations-of-all-mice-weights-control-and-study-groups-of-different-ages-during-all-exper/

Positive feedback of people about my dissertation, blog and YouTube channel by Messenger (Facebook). Feedback positivo de pessoas sobre minha dissertação, blog e canal do YouTube pelo Facebook (Messenger) Year / Ano: 2018 – positive-feedback-of-people-about-my-dissertation-blog-and-youtube-channel-by-facebook-messenger-ano-year-2018

Marios Kyriazis 1

https://pubmed.ncbi.nlm.nih.gov/28185019/

@ ´´A disease is a particular abnormal condition that negatively affects the structure or function of all or part of an organism, and that is not due to any immediate external injury.[1][2] Diseases are often known to be medical conditions that are associated with specific symptoms and signs.[1] A disease may be caused by external factors such as pathogens or by internal dysfunctions. For example, internal dysfunctions of the immune system can produce a variety of different diseases, including various forms of immunodeficiency, hypersensitivity, allergies and autoimmune disorders.´´

When working out which methods to use, researchers should also focus as much as possible on actual problems. People who will duel to the death over abstract theories on the best way to use statistics often agree on results when they are presented with concrete scenarios. Researchers should seek to analyse data in multiple ways to see whether different analyses converge on the same answer. Projects that have crowdsourced analyses of a data set to diverse teams suggest that this approach can work to validate findings and offer new insights. In short, be sceptical, pick a good question, and try to answer it in many ways. It takes many numbers to get close to the truth.´´

http://www.wikipedia.org http://www.gmail.com http://www.yahoo.com http://www.google.com http://www.harvard.edu http://www.nobelprize.org http://www.mit.edu http://www.ucla.edu http://www.stanford.edu http://www.nasa.gov

https://en.wikipedia.org/wiki/Disease

https://en.wikipedia.org/wiki/Research

https://en.wikipedia.org/wiki/Statistics

https://en.wikipedia.org/wiki/Science

* Link about my monograph: Induction of benzonidazole resistance in human isolates of Trypanosoma cruzi: https://science1984.wordpress.com/2018/07/15/my-monography-chagas-disease-research-in-laboratory-2/

-Link about animal models diseases like cardiovascular diseases: https://science1984.wordpress.com/2020/04/29/33426/

– Links related with my dissertation: https://science1984.wordpress.com/2019/11/28/links-of-my-dissertation-the-influence-of-physical-activity-in-the-progression-of-experimental-lung-cancer-in-mice-and-monograph-induction-of-benzonidazole-resistance-in-human-isolates-of-trypanoso/

https://science1984.wordpress.com/2019/11/29/about-my-dissertation-the-influence-of-physical-activity-in-the-progression-of-experimental-lung-cancer-in-mice-pathol-res-pract-2012-jul-152087377-81-doi-10-1016-j-prp-2012-04-006-epub-20/

https://science1984.wordpress.com/2018/07/15/i-did-very-important-detailed-and-innovative-graphics-about-variations-of-all-mice-weigths-during-all-exerimental-time-my-dissertation-they-can-be-an-excelent-reference-for-future-researches-like-2/

https://science1984.wordpress.com/2019/03/08/it-is-fundamental-professors-students-researchers-and-other-people-worldwide-know-about-my-dissertation-because-the-research-was-very-innovative-and-important-in-the-world-these-data-like-graphics/

https://www.diamandis.com/blog/augmenting-immunity-covid-19?utm_campaign=Tech%20Blog&utm_content=122530749&utm_medium=social&utm_source=facebook&hss_channel=fbp-508209262538427&fbclid=IwAR1KqZ9ad9Kng4xseZCs_LoAaedNWIcYBbf5Mk9rNr8qnlWVOWUhuDjiJa8

https://futurism.com/neoscope/fastest-supercomputer-finds-potential-covid-treatments?fbclid=IwAR2fqzaC0rpceufCUtxDLoK9ZIHmHSkaeBhosO2kPOAD7ezw2NTvziPmGqo

https://www.forbes.com/sites/trevornace/2020/03/20/coronavirus-is-growing-faster-in-the-united-states-than-any-other-country-in-the-world/?utm_campaign=forbes&utm_source=facebook&utm_medium=social&utm_term=Valerie%2F&fbclid=IwAR0eqqj1SjQxL9MsHdbzZU69578yF_AB1PXCuPK9mbFTioICN1T9M_5DeXU#4855ef277e72

What Does Statistically Significant Mean?

https://www.nature.com/articles/d41586-019-00874-8

Click to access d41586-019-00874-8.pdf

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EDITORIAL

 

It’s time to talk about ditching statistical significance

Looking beyond a much used and abused measure would make science harder, but better.
 
Bar chart made of measuring cylinders filled with different amounts of varied coloured liquids

Some statisticians are calling for P values to be abandoned as an arbitrary threshold of significance.Credit: Erik Dreyer/Getty

 

3WWW7WWW

 

3ZZZZZZZZZZZZ4ZZZZFans of The Hitchhiker’s Guide to the Galaxy know that the answer to life, the Universe and everything is 42. The joke, of course, is that truth cannot be revealed by a single number.

And yet this is the job often assigned to values: a measure of how surprising a result is, given assumptions about an experiment, including that no effect exists. Whether a P value falls above or below an arbitrary threshold demarcating ‘statistical significance’ (such as 0.05) decides whether hypotheses are accepted, papers are published and products are brought to market. But using P values as the sole arbiter of what to accept as truth can also mean that some analyses are biased, some false positives are overhyped and some genuine effects are overlooked.

Change is in the air. In a Comment in this week’s issue, three statisticians call for scientists to abandon statistical significance. The authors do not call for P values themselves to be ditched as a statistical tool — rather, they want an end to their use as an arbitrary threshold of significance. More than 800 researchers have added their names as signatories. A series of related articles is being published by the American Statistical Association this week (R. L. Wasserstein et al. Am. Stat. https://doi.org/10.1080/00031305.2019.1583913; 2019). “The tool has become the tyrant,” laments one article.

Statistical significance is so deeply integrated into scientific practice and evaluation that extricating it would be painful. Critics will counter that arbitrary gatekeepers are better than unclear ones, and that the more useful argument is over which results should count for (or against) evidence of effect. There are reasonable viewpoints on all sides; Nature is not seeking to change how it considers statistical analysis in evaluation of papers at this time, but we encourage readers to share their views (see go.nature.com/correspondence).

If researchers do discard statistical significance, what should they do instead? They can start by educating themselves about statistical misconceptions. Most important will be the courage to consider uncertainty from multiple angles in every study. Logic, background knowledge and experimental design should be considered alongside values and similar metrics to reach a conclusion and decide on its certainty.

When working out which methods to use, researchers should also focus as much as possible on actual problems. People who will duel to the death over abstract theories on the best way to use statistics often agree on results when they are presented with concrete scenarios.

Researchers should seek to analyse data in multiple ways to see whether different analyses converge on the same answer. Projects that have crowdsourced analyses of a data set to diverse teams suggest that this approach can work to validate findings and offer new insights.

In short, be sceptical, pick a good question, and try to answer it in many ways. It takes many numbers to get close to the truth.

Nature 567, 283 (2019)

doi: 10.1038/d41586-019-00874-8
 

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