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Pathol Res Pract. 2012 Jul 15;208(7):377-81. doi: 10.1016/j.prp.2012.04.006. Epub 2012 Jun 8.
The influence of physical activity in the progression of experimental lung cancer in mice
Renato Batista Paceli 1, Rodrigo Nunes Cal, Carlos Henrique Ferreira dos Santos, José Antonio Cordeiro, Cassiano Merussi Neiva, Kazuo Kawano Nagamine, Patrícia Maluf Cury
- PMID: 22683274
- DOI: 10.1016/j.prp.2012.04.006
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GRUPO_AF1 – GROUP AFA1 – Aerobic Physical Activity – Atividade Física Aeróbia – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto
GRUPO AFAN 1 – GROUP AFAN1 – Anaerobic Physical Activity – Atividade Física Anaeróbia – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto
GRUPO_AF2 – GROUP AFA2 – Aerobic Physical Activity – Atividade Física Aeróbia – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto
GRUPO AFAN 2 – GROUP AFAN 2 – Anaerobic Physical Activity – Atividade Física Anaeróbia – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto
Slides – mestrado – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto
CARCINÓGENO DMBA EM MODELOS EXPERIMENTAIS
DMBA CARCINOGEN IN EXPERIMENTAL MODELS
Avaliação da influência da atividade física aeróbia e anaeróbia na progressão do câncer de pulmão experimental – Summary – Resumo – ´´My´´ Dissertation – Faculty of Medicine of Sao Jose do Rio Preto
Abstract
Lung cancer is one of the most incident neoplasms in the world, representing the main cause of mortality for cancer. Many epidemiologic studies have suggested that physical activity may reduce the risk of lung cancer, other works evaluate the effectiveness of the use of the physical activity in the suppression, remission and reduction of the recurrence of tumors. The aim of this study was to evaluate the effects of aerobic and anaerobic physical activity in the development and the progression of lung cancer. Lung tumors were induced with a dose of 3mg of urethane/kg, in 67 male Balb – C type mice, divided in three groups: group 1_24 mice treated with urethane and without physical activity; group 2_25 mice with urethane and subjected to aerobic swimming free exercise; group 3_18 mice with urethane, subjected to anaerobic swimming exercise with gradual loading 5-20% of body weight. All the animals were sacrificed after 20 weeks, and lung lesions were analyzed. The median number of lesions (nodules and hyperplasia) was 3.0 for group 1, 2.0 for group 2 and 1.5-3 (p=0.052). When comparing only the presence or absence of lesion, there was a decrease in the number of lesions in group 3 as compared with group 1 (p=0.03) but not in relation to group 2. There were no metastases or other changes in other organs. The anaerobic physical activity, but not aerobic, diminishes the incidence of experimental lung tumors.
Copyright © 2012 Elsevier GmbH. All rights reserved.
´´Virtuality is the quality of having the attributes of something without sharing its (real or imagined) physical form.´´ https://en.wikipedia.org/wiki/Virtuality_(disambiguation) @ ´´Reality is the sum or aggregate of all that is real or existent within a system, as opposed to that which is only imaginary. The term is also used to refer to the ontological status of things, indicating their existence.[1] In physical terms, reality is the totality of a system, known and unknown.[2]´´https://en.wikipedia.org/wiki/Reality @ How to Submit research article for SPRINGER NATURE #Naturepublishing #Springer #SNAPPLIED SCIENCES – YouTube Video @ A closer look at the race to develop antibody drugs for COVID-19 – AUTHOR – Ben Fidler @BentheFidler PUBLISHED May 12, 2020 @ CGD NOTES – Leave No One Behind: Using a Benefit-Based Advance Market Commitment to Incentivise Development and Global Supply of COVID-19 Vaccines – MAY 7, 2020 @ Genetics of Covid-19 patients is focus of study – Research into the genetic code of Covid-19 patients could help predict severity of the disease. & MAY 12, 2020 5:51 AM PDT Share – Disabling Genes in Immune Cells Prevents Obesity – WRITTEN BY: Tara Fernandez ´´Obesity is a $1.7 trillion problem in the United States, a condition that leads to several chronic illnesses including heart disease, stroke and certain types of cancer.´´ @ Blood Factors Reverse Epigenetic Age by Half in Rats Steve Hill May 11, 2020 ´´Researchers have demonstrated that epigenetic age can be halved in rats by using signals commonly found in the blood.´´ https://www.lifespan.io/news/blood-factors-reverse-epigenetic-age-by-half-in-rats/
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https://en.wikipedia.org/wiki/Virtuality_(disambiguation)
https://en.wikipedia.org/wiki/Reality
Virtuality (disambiguation)
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Look up virtuality in Wiktionary, the free dictionary. |
Virtuality is the quality of having the attributes of something without sharing its (real or imagined) physical form.
Virtuality also may refer to:
Technology[edit]
- Virtuality (gaming), a family of virtual reality arcade machines.
- Virtuality (software design), a concept of software design proposed by Ted Nelson.
- Reality–virtuality continuum, a concept in computer science.
- Augmented virtuality, the merging of real-world objects into virtual worlds.
- Real Virtuality, a proprietary computer game engine developed by Bohemia Interactive.
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- Virtuality (philosophy)
- Virtuality (song), by Rush
- “Virtuality”, a song by VBirds
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Konrad Kleinknecht
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Konrad Kleinknecht (* 23. April 1940 in Ravensburg) ist ein deutscher Physiker.
Inhaltsverzeichnis
Leben und Werk[Bearbeiten | Quelltext bearbeiten]
Kleinknecht studierte von 1958 bis 1963 Physik an den Universitäten München und Heidelberg. 1966 wurde er in Heidelberg zum Dr. rer. nat. promoviert. Anschließend war er bis 1969 wissenschaftlicher Angestellter am CERN in Genf, dann bis 1972 wissenschaftlicher Assistent an der Universität Heidelberg, wo er sich 1971 habilitierte. 1972 wurde er auf einen Lehrstuhl an der Universität Dortmund berufen, wo er die Fachrichtung Teilchenphysik aufbaute und Dekan, Prodekan sowie Institutsleiter wurde. 1985 wechselte er an die Universität Mainz. Von 1989 bis 1992 war er Vorsitzender des Fachverbandes Teilchenphysik der Deutschen Physikalischen Gesellschaft (DPG) und 1997 bis 1999 Vorstandsmitglied der DPG. Von 2000 bis 2008 beriet er den Vorstand der DPG als Beauftragter für den Klimaschutz.
Kleinknecht arbeitet auf dem Gebiet der experimentellen Elementarteilchenphysik, besonders zur Schwachen Wechselwirkung, zur Neutrinophysik und zur Verletzung der Materie-Antimaterie-Symmetrie. Durch Entwicklungen auf dem Gebiet der Teilchendetektoren gelangen ihm Präzisionsexperimente, insbesondere zur Verletzung der CP-Symmetrie im System neutraler Kaonen. 1988 konnte die NA31 Kollaboration am CERN, deren Mitglied er war, unter Leitung von Heinrich Wahl erste Anzeichen für direkte CP-Verletzung bei Kaonen liefern.[1]
Seit Ende 2012 ist Kleinknecht Gründungsvorsitzender der Heisenberg-Gesellschaft.[2]
Auszeichnungen[Bearbeiten | Quelltext bearbeiten]
- 1984 Neutrino-Medaille der Eötvös-Society (Ungarische physikalische Gesellschaft)
- 1990 Gottfried-Wilhelm-Leibniz-Preis (Deutsche Forschungsgemeinschaft)
- 2001 Gentner-Kastler-Preis (Société française de physique und Deutsche Physikalische Gesellschaft)
- 2005 High Energy and Particle Physics prize (European Physical Society) als Mitglied der NA31 Kollaboration*
- 2008 Stern-Gerlach-Medaille (Deutsche Physikalische Gesellschaft)
* Zur Hälfte an Heinrich Wahl, zur anderen Hälfte an NA31[3]
Veröffentlichungen[Bearbeiten | Quelltext bearbeiten]
Kleinknecht publizierte mehr als 500 wissenschaftliche Arbeiten und teilweise Sachbücher, darunter
- Interferenz zwischen den {\displaystyle \pi ^{+}\pi ^{-}}-Zerfällen der KS und KL-Mesonen und die KS-KL-Massendifferenz. Dissertation, Heidelberg 1966
- Detektoren für Teilchenstrahlung. Teubner Verlag, Stuttgart 1984, ISBN 978-3-519-03058-4, 4. Auflage: Teubner, Wiesbaden 2005, ISBN 3-8351-0058-0
- Detectors for Particle Radiation. Cambridge University Press, Cambridge 1998, 2nd edition
- K. Kleinknecht und T. D. Lee (Hrsg.): Particles and Detectors. Festschrift für Jack Steinberger. Springer, Berlin [u. a.] 1986 (= Springer tracts in modern physics, Band 108), ISBN 3-540-16265-8.
- Uncovering CP Violation. Experimental Clarification in the Neutral K Meson and B Meson Systems. Springer, Berlin [u. a.] 2003 (= Springer Tracts in Modern Physics, Band 195), ISBN 978-3-540-40333-3.
- Wer im Treibhaus sitzt. Piper Verlag München, 2007, ISBN 978-3-492-05011-1
- Quanten, Herausgeber Konrad Kleinknecht, Schriften der Heisenberg-Gesellschaft, Hirzel Verlag Stuttgart, Erstausgabe 2013, Folgebände in den nachfolgenden Jahren ebenfalls im Hirzel Verlag.
- Risiko Energiewende : Wege aus der Sackgasse, Springer Spektrum Verlag, 2015, ISBN 978-3-662-46887-6.
- Einstein und Heisenberg, Begründer der modernen Physik, Kohlhammer Verlag Stuttgart 2017
- Einstein and Heisenberg, The Controversy over Quantum Physics, Springer Nature Publ., 2019, ISBN 978-3-030-05264-5
- Werner Heisenberg – Ordnung der Wirklichkeit, Herausgeber Konrad Kleinknecht, Springer Spektrum Verlag, 2019, ISBN 978-3-662-59529-9
- Werner Heisenberg – Reality and its Order, Konrad Kleinknecht (ed.), Springer Nature Publ., 2019, ISBN 978-3-030-25696-8
- Einstein et Heisenberg, la controverse quantique, 2020
Einzelnachweise[Bearbeiten | Quelltext bearbeiten]
- ↑ NA31 Collaboration: First Evidence for Direct CP Violation. In: Physical Letters B. Band 206, 1988, S. 169.
- ↑ Die Gründung des Vereins. Heisenberg-Gesellschaft e.V., abgerufen am 21. März 2016.
- ↑ Prizes reward high-energy physics. physicsworld, abgerufen am 4. Mai 2019.
Literatur[Bearbeiten | Quelltext bearbeiten]
- Kürschners Deutscher Gelehrten-Kalender. 2007, S. 1793f., ISBN 3-598-23616-6
Weblinks[Bearbeiten | Quelltext bearbeiten]
- Prof. Dr. Konrad Kleinknecht auf uni-mainz.de
- Literatur von und über Konrad Kleinknecht im Katalog der Deutschen Nationalbibliothek
- Arbeiten von Konrad Kleinknecht auf SPIRES
Normdaten (Person): GND: 12847906X | LCCN: n84182940 | VIAF: 93522384 | Wikipedia-PersonensucheKategorien:
- Physiker (20. Jahrhundert)
- Physiker (21. Jahrhundert)
- Hochschullehrer (Technische Universität Dortmund)
- Hochschullehrer (Johannes Gutenberg-Universität Mainz)
- Gentner-Kastler-Preisträger
- Leibnizpreisträger
- Deutscher
- Geboren 1940
- Mann
- Person (CERN)
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Einstein and Heisenberg: The Controversy over Quantum Physics
21 March 2020
Einstein and Heisenberg: The Controversy over Quantum Physics, by Konrad Kleinknecht, Springer

This attractive and exciting book gives easy access to the history of the two main pillars of modern physics of the first half of the 20th century: the theory of relativity and quantum mechanics. The history unfolds along the parallel biographies of the two giants in these fields, Albert Einstein and Werner Heisenberg. It is a fascinating read for everybody interested in the science and culture of their time.
At first sight, one could think that the author presents a twin biography of Einstein and Heisenberg, and that’s all. However, one quickly realises that there is much more to this concise and richly illustrated text. Einstein and Heisenberg’s lives are embedded in the context of their time, with emphasis given to explaining the importance and nature of their interactions with the physicists of rank and name around them. The author cites many examples from letters and documents for both within their respective environments, which are most interesting to read, and illustrate well the spirit of the time. Direct interactions between both heroes of the book were quite sparse though.
At several stages throughout the book, the reader will become familiar with the personal life stories of both protagonists, who were, in spite of some commonalities, very different from each other. Common to both, for instance, was their devotion to music and their early interest and outstanding talent in physics as boys at schools in Munich, but on the contrary they were very different in their relations with family and partners, as the author discusses in a lively way. Many of these aspects are well known, but there are also new facets presented. I liked the way this is done, and, in particular, the author does not shy away from also documenting the perhaps less commendable human aspects, but without judgement, leaving the reader to come to their own conclusion.
Topics covering a broad spectrum are commented on in a special chapter called “Social Affinities”. These include religion, music, the importance of family, and, in the case of Einstein, his relation to his wives and women in general, the way he dealt with his immense public reputation as a super scientist, and also his later years when he could be seen as “scientifically an outsider”. In Heisenberg’s case, one is reminded of his very major contributions to the restoration of scientific research in West Germany and Europe after World War II, not least of course in his crucial founding role in the establishment of CERN.
Do not expect a systematic, comprehensive introduction to relativity and quantum physics; this is not a textbook. Its great value is the captivating way the author illustrates how these great minds formed their respective theories in relation to the physics and academic world of their time. The reader learns not only about Einstein and Heisenberg, but also about many of their contemporary colleagues. A central part in this is the controversy about the interpretation of quantum mechanics among Heisenberg’s colleagues and mentors, such as Schrödinger, Bohr, Pauli, Born and Dirac, to name just a few.
Another aspect of overriding importance for the history of that time was of course the political environment spanning the time from before World War I to after World War II. Both life trajectories were influenced in a major way by these external political and societal factors. The author gives an impressive account of all these aspects, and sheds light on how the pair dealt with these terrible constraints, including their attitudes and roles in the development of nuclear weapons.
A special feature of the book, which will make it interesting to everybody, is the inclusion of various hints as to where relativity and quantum mechanics play a direct role in our daily lives today, as well as in topical contemporary research, such as the recently opened field of gravitational-wave astronomy.
This is an ambitious book, which tells the story of the birth of modern physics in a well-documented and well-illustrated way. The author has managed brilliantly to do this in a serious, but nevertheless entertaining, way, which will make the book a pleasant read for all.
Peter Jenni Albert Ludwig University of Freiburg and CERN
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