Do the downloads!! Share !! Thanks in advance !!
Do the downloads !!! Share!! Thanks!!
´´The world people need to have very efficient researches and projects resulting in very innovative drugs, vaccines, therapeutical substances, medical devices and other technologies according to the age, the genetics and medical records of the person. So, the treatment, diagnosis and prognosis will be very efficient and better, of course´´. Rodrigo Nunes Cal
Mestrado – Dissertation – Tabelas, Figuras e Gráficos – Tables, Figures and Graphics
Informacoes-relevantes-relacionadas-a-leitura-de-livros-e-seus-aspectos-interligados-no-ambiente-escolar-rodrigo-nunes-cal-parte-1 @ Relevant-information-related-book-reading-and-its-interconnected-aspects-in-the-school-environment – Very important links to download eBooks for free – Links muito importantes para baixar e-Books gratuitamente
Informacoes-relevantes-relacionadas-a-leitura-de-livros-e-seus-aspectos-interligados-no-ambiente-escolar-parte-2 @ Relevant-information-related-book-reading-and-its-interconnected-aspects-in-the-school-environment – Very important links to download eBooks for free – Links muito importantes para baixar e-Books gratuitamente
Links-of-this-blog-part-1 – http://www.science1984.com
Links-of-my-blog-part-2 – http://www.science1984.com
My suggestion of a very important Project…
LISTA DE NOMES – PEOPLE´S NAMES – E-MAIL LIST – LISTA DE E-MAILS
CARCINÓGENO DMBA EM MODELOS EXPERIMENTAIS
Mestrado – Dissertation – Tabelas, Figuras e Gráficos – Tables, Figures and Graphics
Textos que digitei – Texts I typed
nanomedicine–an-evolving-research-2155-983X-1000160(2)
Impact_Fator-wise_Top100Science_Journals
redefine-statistical-signifcance
BIOGRAFIA-DOMINGO-MARCOLINO-BRAILE
MÉTODOS DE DOSAGEM DO ÁCIDO HIALURÔNICO
Nanomedicina – Texto que escrevi. Nanomedicine – Text I typed(1)
journal-of-nanomedicine–nanotechnology-flyer
As credenciais da ciência – Mestrado
LISTA DE NOMES – PEOPLE´S NAMES – E-MAIL LIST – LISTA DE E-MAILS
A Psicossomática Psicanalítica
My suggestion of a very important Project…
Frases que digitei – Phrases I typed
DMBA – 7,12–Dimethylbenz[a]anthracene
CARCINÓGENO DMBA EM MODELOS EXPERIMENTAIS
Mestrado – Dissertation – Tabelas, Figuras e Gráficos – Tables, Figures and Graphics
Informacoes-relevantes-relacionadas-a-leitura-de-livros-e-seus-aspectos-interligados-no-ambiente-escolar-rodrigo-nunes-cal-parte-1 @ Relevant-information-related-book-reading-and-its-interconnected-aspects-in-the-school-environment – Very important links to download eBooks for free – Links muito importantes para baixar e-Books gratuitamente
Informacoes-relevantes-relacionadas-a-leitura-de-livros-e-seus-aspectos-interligados-no-ambiente-escolar-parte-2 @ Relevant-information-related-book-reading-and-its-interconnected-aspects-in-the-school-environment – Very important links to download eBooks for free – Links muito importantes para baixar e-Books gratuitamente
Links-of-this-blog-part-1 – http://www.science1984.com
Links-of-my-blog-part-2 – http://www.science1984.com
Mestrado – Dissertation – Tabelas, Figuras e Gráficos – Tables, Figures and Graphics
Impact_Fator-wise_Top100Science_Journals
CARCINÓGENO DMBA EM MODELOS EXPERIMENTAIS
Mestrado – Dissertation – Tabelas, Figuras e Gráficos – Tables, Figures and Graphics
Redefine Statistical Significance
´´We propose to change the default P-value threshold for statistical significance from 0.05 to 0.005 for claims of new discoveries.´´ https://www.nature.com/articles/s41562-017-0189-z Published: Daniel J. Benjamin, James O. Berger, […]Valen E. Johnson Nature Human Behaviour volume 2, pages6–10 (2018)
Um mundo além de p < 0,05 « Sandra Merlo – Fonoaudiologia da Fluência
American Statistical Association – https://www.amstat.org/
https://www.amstat.org/ASA/about/home.aspx?hkey=6a706b5c-e60b-496b-b0c6-195c953ffdbc
Positive Feedbacks by Facebook and Twitter about this Blog, like the very important, innovative and detailed graphics I did about variations of all mice weights (Control and Study Groups) of different ages during all experimental time of ´´my´´ dissertation. Note: I have received positive feedbacks about this Blog by LinkedIn, E-mails and Instagram too. @ Internet invitations I received by direct messages to participate in very important science events worldwide in less than 1 year because I participated of great researches in Brazil and other informations @ Links & The next step in nanotechnology | George Tulevski & Animated Nanomedicine movie @ Nanotechnology Animation & Powering Nanorobots & The World’s Smallest Robots: Rise of the Nanomachines & Building Medical Robots, Bacteria sized: Bradley Nelson at TEDxZurich @ Mind-controlled Machines: Jose del R. Millan at TEDxZurich & The present and future of brain-computer interfaces: Avi Goldberg at TEDxAsheville & Future of human/computer interface: Paul McAvinney at TEDxGreenville 2014 @ Bio-interfaced nanoengineering: human-machine interfaces | Hong Yeo | TEDxVCU @ Very important images, websites, social networks and links – https://science1984.wordpress.com/2019/03/17/feedbacks-on-facebook-related-to-researches-i-participated-in-brazil-for-example-the-graphics-i-did-about-variations-of-all-mice-weights-control-and-study-groups-of-different-ages-during-all-exper/
Positive feedback of people about my dissertation, blog and YouTube channel by Messenger (Facebook). Feedback positivo de pessoas sobre minha dissertação, blog e canal do YouTube pelo Facebook (Messenger) Year / Ano: 2018 – positive-feedback-of-people-about-my-dissertation-blog-and-youtube-channel-by-facebook-messenger-ano-year-2018
http://www.google.com http://www.gmail.com http://www.yahoo.com http://www.forbes.com http://www.facebook.com http://www.twitter.com http://www.linkedin.com http://www.youtube.com http://www.cnn.com http://www.bbc.com http://www.usa.gov http://www.instagram.com http://www.wikipedia.org http://www.wordpress.com http://www.harvard.edu http://www.mit.edu
http://www.apple.com http://www.nobelprize.org http://www.nasa.gov http://www.microsoft.com http://www.amazon.com http://www.alibaba.com http://www.stanford.edu http://www.ucla.edu http://www.michigan.edu http://www.caltech.edu http://www.yale.edu http://www.columbia.edu http://www.duke.edu http://www.famerp.br http://www.ita.br http://www.embraer.com
http://www.unicamp.br http://www.twitter.com/CalZole http://www.cornell.edu http://www.uftm.edu.br/
https://www.indispensablesoma.info/who-is-marios-kyriazis
https://www.indispensablesoma.info/general-facts
My Facebook Page: http://www.facebook.com/scientificblog
https://www.facebook.com/marios.kyriazis/
https://www.visitcyprus.com/index.php/ru/news/195-kyriazis-the-museum-the-man-and-the-medicine
https://www.linkedin.com/pulse/my-interview-man-year-scientist-2017-marios-kyriazis/
Biogerentology.2017 Aug;18(4):711-715. doi: 10.1007/s10522-017-9680-1. Epub 2017 Feb 9.
Biological ageing and clinical consequences of modern technology
https://pubmed.ncbi.nlm.nih.gov/28185019/
Who are the top 10 pharmaceutical companies in the world? (2020)
11/08/2020 Hannah Burke
https://www.proclinical.com/blogs/2020-8/the-top-10-pharmaceutical-companies-in-the-world-2020
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Ty Haqqi
September 13, 2020
https://finance.yahoo.com/news/10-biggest-pharmaceutical-companies-world-184321012.html
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Pharm Exec’s Top 50 Companies 2020
July 9, 2020Michael Christel
Pharmaceutical Executive, Pharmaceutical Executive-06-01-2020, Volume 40, Issue 6
https://www.pharmexec.com/view/pharm-execs-top-50-companies-2020
google-site-verification=ZCx0AbfQWbzm-iXvCsaBE21zojBkOqDC-XbLhIL9rU8
https://en.wikipedia.org/wiki/Disease https://en.wikipedia.org/wiki/Physiology
https://en.wikipedia.org/wiki/Nobel_Prize_in_Physiology_or_Medicine
https://en.wikipedia.org/wiki/DNA
https://en.wikipedia.org/wiki/Central_dogma_of_molecular_biology#Biological_sequence_information
https://en.wikipedia.org/wiki/Evolution https://en.wikipedia.org/wiki/Gene
https://en.wikipedia.org/wiki/Biology https://en.wikipedia.org/wiki/Life
https://en.wikipedia.org/wiki/Cell_(biology) https://en.wikipedia.org/wiki/Energy
https://en.wikipedia.org/wiki/RNA https://en.wikipedia.org/wiki/Genome
http://www.google.com http://www.gmail.com http://www.yahoo.com http://www.forbes.com http://www.youtube.com http://www.wordpress.com http://www.nobelprize.org http://www.youtube.com http://www.nobelprize.org
https://en.wikipedia.org/wiki/Protein_biosynthesis https://en.wikipedia.org/wiki/Oncogene
https://en.wikipedia.org/wiki/RNA-dependent_RNA_polymerase
https://en.wikipedia.org/wiki/Nucleotide https://en.wikipedia.org/wiki/Gene_product
https://en.wikipedia.org/wiki/Peptide https://en.wikipedia.org/wiki/Information
https://en.wikipedia.org/wiki/RNA_polymerase https://en.wikipedia.org/wiki/Research
https://en.wikipedia.org/wiki/Gene_expression https://en.wikipedia.org/wiki/Nature_(journal)
https://en.wikipedia.org/wiki/Enzyme https://en.wikipedia.org/wiki/Central_dogma_of_molecular_biology
https://en.wikipedia.org/wiki/Metabolism https://en.wikipedia.org/wiki/Virus
https://en.wikipedia.org/wiki/Cachexia https://en.wikipedia.org/wiki/Scientific_journal
https://en.wikipedia.org/wiki/Cancer https://en.wikipedia.org/wiki/Data
https://en.wikipedia.org/wiki/Weight_loss https://en.wikipedia.org/wiki/Science_(journal)
https://en.wikipedia.org/wiki/Overweight https://en.wikipedia.org/wiki/Academic_journal
https://en.wikipedia.org/wiki/Peptide_bond https://en.wikipedia.org/wiki/Organism
https://en.wikipedia.org/wiki/Small_nuclear_RNA https://en.wikipedia.org/wiki/Small_nucleolar_RNA
https://en.wikipedia.org/wiki/Biological_activity https://en.wikipedia.org/wiki/Drug_discovery
https://en.wikipedia.org/wiki/Biotechnology https://en.wikipedia.org/wiki/Genomics
https://en.wikipedia.org/wiki/Genetics https://en.wikipedia.org/wiki/Genetic_variation
https://en.wikipedia.org/wiki/Mutation https://en.wikipedia.org/wiki/Viral_replication
https://en.wikipedia.org/wiki/Mobile_genetic_elements https://en.wikipedia.org/wiki/Genetic_recombination
https://en.wikipedia.org/wiki/ https://en.wikipedia.org/wiki/Apoptosis
https://en.wikipedia.org/wiki/Necrosis https://en.wikipedia.org/wiki/Cell_damage
https://en.wikipedia.org/wiki/Death https://en.wikipedia.org/wiki/Time
https://en.wikipedia.org/wiki/Health https://en.wikipedia.org/wiki/Ageing
https://en.wikipedia.org/wiki/Population_ageing https://en.wikipedia.org/wiki/Median
https://en.wikipedia.org/wiki/Probability_theory https://en.wikipedia.org/wiki/Mathematics
https://en.wikipedia.org/wiki/Probability_interpretations https://en.wikipedia.org/wiki/Frequentist_probability https://en.wikipedia.org/wiki/Limit_of_a_sequence https://en.wikipedia.org/wiki/Mathematical_analysis
https://en.wikipedia.org/wiki/Robust_statistics#resistant_statistic
https://en.wikipedia.org/wiki/Robust_statistics#Breakdown_point https://en.wikipedia.org/wiki/Data_set https://en.wikipedia.org/wiki/Table_(database)
https://en.wikipedia.org/wiki/Relational_database https://en.wikipedia.org/wiki/Relational_model
https://en.wikipedia.org/wiki/Relation_(database) https://en.wikipedia.org/wiki/Data_type
https://en.wikipedia.org/wiki/Computer_science https://en.wikipedia.org/wiki/Computational_problem
https://en.wikipedia.org/wiki/Computer https://en.wikipedia.org/wiki/Machine https://en.wikipedia.org/wiki/Multicellular_organism
https://en.wikipedia.org/wiki/Molecular_evolution
https://en.wikipedia.org/wiki/Working_animal https://en.wikipedia.org/wiki/Human_power
https://en.wikipedia.org/wiki/Human_body https://en.wikipedia.org/wiki/Human https://en.wikipedia.org/wiki/Eukaryote
https://en.wikipedia.org/wiki/Species https://en.wikipedia.org/wiki/Tissue_(biology) https://en.wikipedia.org/wiki/Prokaryote https://en.wikipedia.org/wiki/Protein
https://en.wikipedia.org/wiki/Organ_(anatomy) https://en.wikipedia.org/wiki/Unicellular_organism
Phases of clinical research: https://en.wikipedia.org/wiki/Phases_of_clinical_research
´´The phases of clinical research are the stages in which scientists conduct experiments with a health intervention to obtain sufficient evidence for a process considered effective as a medical treatment.[1] For drug development, the clinical phases start with testing for safety in a few human subjects, then expand to many study participants (potentially tens of thousands) to determine if the treatment is effective.[1] Clinical research is conducted on drug candidates, vaccine candidates, new medical devices, and new diagnostic assays.´´
´´Clinical trials testing potential medical products are commonly classified into four phases. The drug development process will normally proceed through all four phases over many years.[1] If the drug successfully passes through Phases I, II, and III, it will usually be approved by the national regulatory authority for use in the general population.[1] Phase IV trials are ‘post-marketing’ or ‘surveillance’ studies conducted to monitor safety over several years.[1]´´
´´Before clinical trials are undertaken for a candidate drug, vaccine, medical device, or diagnostic assay, the product candidate is tested extensively in preclinical studies.[1] Such studies involve in vitro (test tube or cell culture) and in vivo (animal model) experiments using wide-ranging doses of the study agent to obtain preliminary efficacy, toxicity and pharmacokinetic information. Such tests assist the developer to decide whether a drug candidate has scientific merit for further development as an investigational new drug.[1]´´
https://en.wikipedia.org/wiki/Model_organism
´´Genomic data is used to make close comparisons between species and determine relatedness. As humans, we share about 99% of our genome with chimpanzees[57][58] (98.7% with bonobos)[59] and over 90% with the mouse.[56] With so much of the genome conserved across species, it is relatively impressive that the differences between humans and mice can be accounted for in approximately six thousand genes (of ~30,000 total). Scientists have been able to take advantage of these similarities in generating experimental and predictive models of human disease.´´
The Drug Development Process – https://www.fda.gov/patients/learn-about-drug-and-device-approvals/drug-development-process
Step 1: Discovery and Development: https://www.fda.gov/patients/drug-development-process/step-1-discovery-and-development
Step 2: Preclinical Research: https://www.fda.gov/patients/drug-development-process/step-2-preclinical-research
Step 3: Clinical Research: https://www.fda.gov/patients/drug-development-process/step-3-clinical-research
Step 4: FDA Drug Review: https://www.fda.gov/patients/drug-development-process/step-4-fda-drug-review
Step 5: FDA Post-Market Drug Safety Monitoring: https://www.fda.gov/patients/drug-development-process/step-5-fda-post-market-drug-safety-monitoring
Drug development – https://www.sciencedirect.com/topics/nursing-and-health-professions/drug-development#:~:text=Drug%20development%20is%20the%20process,commercial%20launch%20of%20the%20drug.
Drug development: https://en.wikipedia.org/wiki/Drug_development
Drug Discovery and Development Process
Exploring the Drug Development Process – ARTICLE Mar 13, 2020 | By Laura Elizabeth Lansdowne, Senior Science Writer, Technology Networks – https://www.technologynetworks.com/drug-discovery/articles/exploring-the-drug-development-process-331894
Drug Development Research – https://onlinelibrary.wiley.com/journal/10982299
Drug development
Drug development describes the process of developing a new drug that effectively targets a specific weakness in a cell. This process involves specific pre-clinical development and testing, followed by trials in humans to determine the efficacy of the drug.
https://www.nature.com/subjects/drug-development
Phases of New Drug Development
The Importance of Clinical Trials in Drug Development – Avicenna J Med Biotechnol. 2016 Oct-Dec; 8(4): 151. Shahin Akhondzadeh, Ph.D., FBPharmacolS, Editor in Chief
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124250/
Stages of Drug Development: https://pacificbiolabs.com/stages-of-drug-development
Centers for Disease Control and Prevention – https://www.cdc.gov/
- Vaccine Testing and the Approval Process: https://www.cdc.gov/vaccines/basics/test-approve.html
Development of New Vaccines
Vaccine Product Approval Process
Tracking Side Effects Once a Vaccine is Administered
Related Topics and Sources
Related Topics and Sources: https://www.cdc.gov/vaccines/vac-gen/default.htm
For Specific Groups of People: https://www.cdc.gov/vaccines/spec-grps.html
Price Lists and Vaccine Codes: https://www.cdc.gov/vaccines/imz-managers/lists-codes.html
Vaccine Safety: https://www.cdc.gov/vaccinesafety/index.html
Guidelines and Publications: https://www.cdc.gov/vaccines/imz-managers/guides-pubs/index.html
https://www.cdc.gov/vaccines/imz-managers/contacts/index.html
https://www.cdc.gov/vaccines/vaxview/index.html
https://www.cdc.gov/vaccines/imz-managers/laws/index.html
https://www.cdc.gov/vaccines/imz-managers/program-components/index.html
https://www.cdc.gov/vaccines/imz-managers/awardee-imz-websites.html
https://www.cdc.gov/vaccines/pregnancy/index.html
https://www.cdc.gov/vaccines/parents/index.html
https://www.cdc.gov/vaccines/adults/index.html
https://www.cdc.gov/vaccines/hcp/index.html
https://www.cdc.gov/vaccines/covid-19/index.html
https://www.cdc.gov/vaccines/imz-managers/index.html
Vaccines and Preventable Diseases: https://www.cdc.gov/vaccines/vpd/index.html
https://www.cdc.gov/vaccines/news/index.html
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https://www.fredhutch.org/en/faculty-lab-directory/lyman-gary.html
https://www.fredhutch.org/en/about/contact-us.html
https://www.uwmedicine.org/bios/gary-lyman
https://depts.washington.edu/oncology/faculty/lyman.html
https://www.researchgate.net/profile/Gary_Lyman
https://www.linkedin.com/in/gary-lyman-a4811a5/
https://medicine.duke.edu/faculty/gary-herbert-lyman-md
https://www.fredhutch.org/en/faculty-lab-directory/lyman-gary/lyman-spotlight.html
